Senescent Cells
Cells that have stopped dividing but do not die off normally. They can build up with age and release signals that promote inflammation.
Senescent cells are damaged or stressed cells that enter a shutdown state. They no longer divide, which can help prevent cancer, but they can also linger in tissue instead of being cleared.
When too many accumulate, they may disrupt nearby healthy cells by releasing inflammatory signals and tissue-altering molecules. That is why they are central to senolytic research.
Worth Knowing
Senescent cells are not automatically bad in every situation. In the short term they can help with wound healing or tumor suppression. The concern is persistent buildup, not the existence of the state itself.
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Research publication: Definitions reflect current research status and are for educational purposes. This is not medical advice.